Mole Minions are a major enemy found in the Lost City. They are unusually fragile for a major enemy with only four hit points but they still take reduced damage from the Alchemy Coin and the War Horn. Mole Minions have two attacks; the first functions similarly to the ranged attack of the Griffoth except that it has two streams of fireballs that interweave. The other is to have a blade emerge from their weapon followed by a forward thrust. Since they are positioned beneath ceilings this attack renders them vulnerable to the shovel drop.

In Specter of Torment after Mole Knight's defeat one could be seen attending Creech's bar.